Zyban, also known by its generic name Bupropion, is an atypical antidepressant used as a smoking cessation aid. It works by reducing cravings and withdrawal symptoms associated with quitting smoking. It is believed to work by altering the levels of certain chemicals in the brain, specifically dopamine and norepinephrine. Zyban is typically taken for 7 to 12 weeks. Zyban has been shown to increase the chances of successfully quitting smoking when used as part of a comprehensive smoking cessation program.
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Medication Information Leaflet for Zyban
Zyban is a medication used to help quit smoking by reducing withdrawal symptoms and cravings for nicotine.
Generic Ingredient and Its Availability
The generic ingredient of Zyban is bupropion hydrochloride. It is available both as a prescription and over-the-counter medication.
Zyban has been certified by regulatory bodies in the United States, European Union, and Australia.
Zyban belongs to the class of medications known as antidepressants.
Zyban is used in smoking cessation programs as an aid to quit smoking.
Spectrum of Activity
Zyban works by inhibiting the reuptake of norepinephrine and dopamine, which helps to reduce cravings for nicotine.
Known Alternatives in Australia
Some known alternatives to Zyban in Australia include nicotine replacement therapy (NRT) and other medications such as Champix.
Zyban should not be used in combination with other medications that contain bupropion or with monoamine oxidase inhibitors (MAOIs).
Contraindications and Precautions
Zyban is contraindicated in patients with a history of seizures, anorexia or bulimia nervosa, and those undergoing abrupt discontinuation of alcohol or sedatives. Precautions should be taken for patients with liver or kidney disease, patients with a history of bipolar disorder or psychosis, and for those taking medications that lower the seizure threshold.
Possible Side Effect(s)
The most common side effects of Zyban include dry mouth, difficulty sleeping, headaches, and nausea. More serious side effects may include seizures, hallucinations, and suicidal thoughts.
Dosage and Directions
The recommended dosage of Zyban is 150mg once daily for three days, then 150mg twice daily for 7 to 12 weeks. It is recommended to begin taking Zyban one to two weeks before the quit date.
Missed Dose and Overdose
If a dose is missed, it should be taken as soon as possible. If it is close to the time for the next dose, the missed dose should be skipped. Overdose symptoms may include seizures, hallucinations, and loss of consciousness. In case of overdose, seek immediate medical attention.
Zyban should be stored at room temperature away from moisture and heat.
Known Non-standard Use
Zyban has also been used for the treatment of depression, attention deficit hyperactivity disorder (ADHD), and obesity.
Before starting Zyban, patients should inform their healthcare provider if they have a history of seizures or eating disorders, or if they are pregnant or breastfeeding. Patients should also inform their provider of any other medications they are taking.
Breastfeeding and Pregnancy
Zyban should not be used during pregnancy or breastfeeding, as it can be passed on to the baby through breast milk.
The use of Zyban may increase the risk of suicidal thoughts, especially in young adults and adolescents. Patients should be closely monitored for any signs of depression, anxiety, or suicidal thoughts.
- How does Zyban work?
- How long should I take Zyban for?
- Can I still smoke while taking Zyban?
- Are there any serious side effects of Zyban?
- Can I drink alcohol while taking Zyban?
- What should I do if I miss a dose of Zyban?
- Is it safe to take Zyban during pregnancy?
- Can Zyban be used for other medical conditions?
- How does Zyban compare to other smoking cessation aids?
- How effective is Zyban at helping individuals quit smoking?
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