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Arava
Arava

1.9
Used to address pain and inflammation and autoimmune conditions, this generic medicine inhibits specific enzymes involved in the inflammatory response to reduce joint damage.
Ingredient
Leflunomide
Categories
Pain & Anti-Inflammatories, Autoimmune Support
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Leflunomide
Reference Brand
Leflunomide
Product Origin
Generic Alternative
Reference Manufacturer
Sanofi-Aventis
Product Form
Tablet
Regulatory Classification
Prescription Only Medicine
Primary Category
Pain Relief, Autoimmune Support
Product Category
Disease-Modifying Antirheumatic Drug (DMARD)
Pharmacological Class
Pyrimidine Synthesis Inhibitor
Clinical Indications
Active rheumatoid arthritis
Manufacturer Description
Formulated to alleviate joint inflammation to support physical mobility and target progressive skeletal damage.
Mechanism of Action
Inhibits the mitochondrial enzyme dihydroorotate dehydrogenase, blocking pyrimidine synthesis and suppressing autoimmune T-cell proliferation.
Route of Administration
Oral
Onset Time
4–8 weeks
Duration
1–2 weeks
Contraindications
Pregnancy, Severe hepatic impairment, Severe immunodeficiency
Severe Adverse Events
Severe hepatotoxicity — requires immediate medical attention, Pancytopenia — requires immediate medical attention
Common Side Effects
Diarrhea, Nausea, Headache
Uncommon Side Effects
Hair thinning, Elevated liver enzymes, Elevated blood pressure
Drug Interactions
Cholestyramine, Warfarin, Methotrexate
Pregnancy Safety Warnings
TGA Category X: Highly teratogenic. Do not use under any circumstances during pregnancy. Breastfeeding: Contraindicated.
Age Restrictions
Approved for adults.
Storage Guidelines
Store below 25°C.
Related Products
Methotrexate, Imuran
Information related to Arava is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
Categories
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