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Samsca
Samsca

10.13
A generic medicine indicated for hormonal and menopause conditions. Addresses water balance within body tissues by selectively blocking arginine vasopressin receptors to maintain electrolyte stability.
Ingredient
Tolvaptan
Category
Hormone Therapy
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Tolvaptan
Reference Brand
Tolvaptan
Product Origin
Generic Alternative
Reference Manufacturer
Otsuka Pharmaceutical
Product Form
Tablet
Regulatory Classification
Prescription Only Medicine
Primary Category
Hormones
Product Category
Selective Vasopressin V2 Receptor Antagonist
Pharmacological Class
Vasopressin Antagonist
Manufacturer Description
Developed to mitigate severe water overload to support systemic sodium concentration levels and target fluid volume control.
Mechanism of Action
Antagonizes renal V2 receptors, preventing water reabsorption to promote excretion of free water without electrolyte loss.
Route of Administration
Oral
Onset Time
2–4 hours
Duration
24 hours
Contraindications
Urgent need to raise serum sodium, Inability to sense or respond to thirst, Hypovolemic hyponatremia
Severe Adverse Events
Osmotic demyelination syndrome — requires immediate medical attention, Severe hepatotoxicity — requires immediate medical attention
Common Side Effects
Dry mouth, Thirst, Polyuria
Uncommon Side Effects
Pollakiuria, Hyperglycemia, Constipation
Drug Interactions
Ketoconazole, Clarithromycin, Grapefruit
Pregnancy Safety Warnings
TGA Category C: Use if potential benefits outweigh risks. Breastfeeding: Avoid.
Age Restrictions
Approved for adults.
Storage Guidelines
Store below 25°C.
Related Products
DDAVP spray
Information related to Samsca is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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