A generic medicine indicated for hormonal and menopause conditions. Addresses overactive thyroid hormone production by preventing the formation of excessive hormones within the gland.
Intended to relieve hyperthyroidism by managing active thyroid hormone synthesis and supporting cardiovascular stability.
Mechanism of Action
Inhibits thyroid peroxidase, preventing the iodination of tyrosine and synthesis of thyroid hormones.
Route of Administration
Oral
Onset Time
1–2 weeks
Duration
12–24 hours
Contraindications
Severe bone marrow depression, History of methimazole-induced pancreatitis
Severe Adverse Events
Agranulocytosis — requires immediate medical attention, Acute pancreatitis — requires immediate medical attention, Severe hepatotoxicity — requires immediate medical attention
Common Side Effects
Nausea, Headache, Skin rash
Uncommon Side Effects
Joint pain, Taste disturbances, Loss of hair
Drug Interactions
Warfarin, Theophylline, Digoxin
Pregnancy Safety Warnings
TGA Category D: High risk of fetal cutis aplasia in first trimester; propylthiouracil preferred. Breastfeeding: Monitor infant.
Information related to Tapazole is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
