Intended to relieve gastrointestinal bacterial infections to support mucosal structure recovery and target bowel pathogens.
Mechanism of Action
Inhibits bacterial cell wall synthesis by binding to D-alanyl-D-alanine, preventing peptidoglycan cross-linking in susceptible gram-positive bacteria.
Route of Administration
Oral
Onset Time
12–24 hours
Duration
12 hours
Contraindications
Severe renal failure (requires therapeutic drug monitoring), Hypersensitivity to vancomycin
Severe Adverse Events
Nephrotoxicity — requires immediate medical attention, Ototoxicity — requires immediate medical attention, Red man syndrome (if infused rapidly) — requires immediate medical attention
Common Side Effects
Nausea, Headache, Taste changes
Uncommon Side Effects
Mild abdominal pain, Diarrhea, Flatulence
Drug Interactions
Aminoglycosides, Furosemide, Metformin
Pregnancy Safety Warnings
TGA Category B: Safe as it has zero systemic absorption from the gastrointestinal tract. Breastfeeding: Compatible.
Information related to Vancomycin is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
